0000950134-07-013587 Sample Contracts

SECURITIES PURCHASE AGREEMENT Dated as of June 17, 2007 between Lexicon Pharmaceuticals, Inc. and Invus, L.P.
Securities Purchase Agreement • June 19th, 2007 • Lexicon Pharmaceuticals, Inc./De • Pharmaceutical preparations • New York

This SECURITIES PURCHASE AGREEMENT, dated as of June 17, 2007 (this “Agreement”), among Invus, L.P., a Bermuda limited partnership (the “Investor”) and Lexicon Pharmaceuticals, Inc., a Delaware corporation (the “Company”).

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WARRANT AGREEMENT Dated as of June 17, 2007 among Lexicon Pharmaceuticals, Inc. and Invus, L.P.
Warrant Agreement • June 19th, 2007 • Lexicon Pharmaceuticals, Inc./De • Pharmaceutical preparations • New York

WARRANT AGREEMENT (the “Agreement”) dated as of June 17, 2007 among Lexicon Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and Invus, L.P., a Bermuda limited partnership or its permitted assigns (the “Investor”).

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