0000950135-05-005613 Sample Contracts

INVESTMENT AND EXCHANGE AGREEMENT
Investment and Exchange Agreement • September 30th, 2005 • Emisphere Technologies Inc • Pharmaceutical preparations

THIS AGREEMENT (this “Agreement”) is made as of September 26, 2005, by and between Emisphere Technologies, Inc., a Delaware corporation (the “Company”), and (i) MHR Capital Partners (500) LP, a Delaware limited partnership, (ii) MHR Capital Partners (100) LP, a Delaware limited partnership, (iii) MHR Institutional Partners II LP, a Delaware limited partnership and (iv) MHR Institutional Partners IIA LP, a Delaware limited partnership (collectively, and including any of their respective Affiliates (as defined below), the “Investor”).

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EXHIBIT 10.7 PLEDGE AND SECURITY AGREEMENT DATED AS OF SEPTEMBER 26, 2005
Pledge and Security Agreement • September 30th, 2005 • Emisphere Technologies Inc • Pharmaceutical preparations • New York
SENIOR SECURED TERM LOAN AGREEMENT U.S.$15,000,000 Dated as of September 26, 2005 between EMISPHERE TECHNOLOGIES, INC., as Borrower and MHR INSTITUTIONAL PARTNERS IIA LP, as Lender
Senior Secured Term Loan Agreement • September 30th, 2005 • Emisphere Technologies Inc • Pharmaceutical preparations

This SENIOR SECURED TERM LOAN AGREEMENT (this “Agreement”) dated as of September 26, 2005 between Emisphere Technologies, Inc., a Delaware corporation (the “Borrower”) and MHR Institutional Partners IIA LP, a Delaware limited partnership (the “Lender”).

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