0000950135-07-006801 Sample Contracts

Third Amendment to Research Development and Commercialization Agreement Between EPIX Pharmaceuticals, Inc. (“EPIX”) and Cystic Fibrosis Foundation Therapeutics Incorporated (“CFFT”)
Research Development and Commercialization Agreement • November 7th, 2007 • EPIX Pharmaceuticals, Inc. • Pharmaceutical preparations

This Third Amendment (this “Third Amendment”) to the Agreement of March 7, 2005 (as amended, the “Agreement”) is made as of this first day of November, 2007 (the “Effective Date”), by and between EPIX (as successor-in-interest to Predix) and CFFT. Capitalized terms used but not defined herein shall have the definition provided in the Agreement.

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