0000950148-06-000152 Sample Contracts

MANNKIND CORPORATION Issuer And WELLS FARGO BANK, N.A. Trustee FIRST SUPPLEMENTAL INDENTURE Dated as of December 12, 2006

First Supplemental Indenture • December 12th, 2006 • Mannkind Corp • Pharmaceutical preparations • New York

• Contract Type
  First Supplemental Indenture
• Filed
  December 12th, 2006
• Company
  Mannkind Corp
• Industry
  Pharmaceutical preparations
• Jurisdiction
  New York

THIS FIRST SUPPLEMENTAL INDENTURE (this “First Supplemental Indenture”), dated as of December 12, 2006, is between MannKind Corporation, a corporation duly organized under the laws of the State of Delaware (the “Company”), and Wells Fargo Bank, N.A., as Trustee (the “Trustee”).