0000950149-06-000268 Sample Contracts

May 3, 2006 VIA HAND DELIVERY Scott M. Freeman, M.D. Onyx Pharmaceuticals, Inc. 2100 Powell Street Emeryville, CA 94608 Dear Scott:

Separation Agreement • May 12th, 2006 • Onyx Pharmaceuticals Inc • Biological products, (no disgnostic substances) • California

• Contract Type
  Separation Agreement
• Filed
  May 12th, 2006
• Company
  Onyx Pharmaceuticals Inc
• Industry
  Biological products, (no disgnostic substances)
• Jurisdiction
  California

This letter sets forth the terms of our agreement with respect to the termination of your employment with Onyx Pharmaceuticals, Inc. (“Onyx” or the “Company”).