0000950157-14-001045 Sample Contracts

THIRD SUPPLEMENTAL INDENTURE

Third Supplemental Indenture • September 29th, 2014 • Intermune Inc • Pharmaceutical preparations • New York

• Contract Type
  Third Supplemental Indenture
• Filed
  September 29th, 2014
• Company
  Intermune Inc
• Industry
  Pharmaceutical preparations
• Jurisdiction
  New York

This Third Supplemental Indenture (“Third Supplemental Indenture”) is dated as of September 29, 2014 among InterMune, Inc., a Delaware corporation (the “Issuer”), Roche Holdings, Inc., a Delaware corporation (the “Parent”), and The Bank of New York Mellon Trust Company, N.A., a national banking association, as trustee under the Indenture defined below (the “Trustee”).

FOURTH SUPPLEMENTAL INDENTURE

Fourth Supplemental Indenture • September 29th, 2014 • Intermune Inc • Pharmaceutical preparations • New York

• Contract Type
  Fourth Supplemental Indenture
• Filed
  September 29th, 2014
• Company
  Intermune Inc
• Industry
  Pharmaceutical preparations
• Jurisdiction
  New York

This Fourth Supplemental Indenture (“Fourth Supplemental Indenture”) is dated as of September 29, 2014 among InterMune, Inc., a Delaware corporation (the “Issuer”), Roche Holdings, Inc., a Delaware corporation (the “Parent”), and The Bank of New York Mellon Trust Company, N.A., a national banking association, as trustee under the Indenture defined below (the “Trustee”).