0000950170-23-041394 Sample Contracts

IDEAYA BIOSCIENCES, INC. AMENDED AND RESTATED EMPLOYMENT AGREEMENT
Employment Agreement • August 10th, 2023 • IDEAYA Biosciences, Inc. • Pharmaceutical preparations • California

This Amended and Restated Employment Agreement (the “Agreement”) is entered into between IDEAYA Biosciences, Inc., a Delaware corporation (the “Company”) and Andres Ruiz Briseno (“Executive” and, together with the Company, the “Parties”) effective as of July 1, 2023 (the “Effective Date”). This Agreement supersedes in its entirety that certain Employment Agreement between Executive and the Company dated as of November 1, 2021 (“Prior Agreement”).

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Amendment No. 1 to Agreement (“Amendment No. 1”)
Clinical Trial Collaboration and Supply Agreement • August 10th, 2023 • IDEAYA Biosciences, Inc. • Pharmaceutical preparations

WHEREAS, the Parties entered into the Agreement, for the Global Phase 2, registration enabling study in Metastatic Uveal Melanoma (MUM) and GNAQ/11-mutated Solid Tumors (non-MUM) pertaining to the clinical evaluation of the Ideaya Compound in combination with the Pfizer Compound;

LEASE BY AND BETWEEN DW LSP 5000 SHORELINE, LLC, a Delaware limited liability company as Landlord and IDEAYA BIOSCIENCES, INC. a Delaware corporation as Tenant For Premises located at 5000 Shoreline Court South San Francisco, California
Lease Agreement • August 10th, 2023 • IDEAYA Biosciences, Inc. • Pharmaceutical preparations

This Lease is dated as of the lease reference date specified in Section A of the Summary of Basic Lease Terms and is made by and between the party identified as Landlord in Section B of the Summary and the party identified as Tenant in Section C of the Summary.

Amendment No. 4 to Agreement (“Amendment No. 4”)
Clinical Trial Collaboration and Supply Agreement • August 10th, 2023 • IDEAYA Biosciences, Inc. • Pharmaceutical preparations

Name of Original Agreement: Clinical Trial Collaboration and Supply Agreement (the “Original Agreement,” and together with any previous amendments which may be described below, the “Agreement”)

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