0000950170-24-017879 Sample Contracts

Name: Number of Shares of Stock subject to Stock Option: Price Per Share: Date of Grant: Vesting Start Date:
Stock Option Agreement • February 21st, 2024 • Ultragenyx Pharmaceutical Inc. • Pharmaceutical preparations

Ultragenyx Pharmaceutical Inc. 2023 Incentive PlanNon-statutory Stock Option Agreement (Directors) This agreement (this “Agreement”) evidences a stock option granted by Ultragenyx Pharmaceutical Inc. (the “Company”) to the undersigned (the “Optionee”) pursuant to and subject to the terms of the Ultragenyx Pharmaceutical Inc. 2023 Incentive Plan (as amended from time to time, the “Plan”), which is incorporated herein by reference. 1.Grant of Stock Option. The Company grants to the Optionee on the date set forth above (the “Date of Grant”) an option (the “Stock Option”) to purchase, on the terms provided herein and in the Plan, up to the number of shares of Stock set forth above (the “Shares”) with an exercise price per Share as set forth above, in each case subject to adjustment pursuant to Section 7(b) of the Plan in respect of transactions occurring after the date hereof. 2.Meaning of Certain Terms. Except as otherwise defined herein, all capitalized terms used herein have the same me

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Name: Number of Shares of Stock subject to Stock Option: Price Per Share: Date of Grant: Vesting Start Date:
Stock Option Agreement • February 21st, 2024 • Ultragenyx Pharmaceutical Inc. • Pharmaceutical preparations

Ultragenyx Pharmaceutical Inc. 2023 Incentive Planincentive Stock Option Agreement This agreement (this “Agreement”) evidences a stock option granted by Ultragenyx Pharmaceutical Inc. (the “Company”) to the undersigned (the “Optionee”) pursuant to and subject to the terms of the Ultragenyx Pharmaceutical Inc. 2023 Incentive Plan (as amended from time to time, the “Plan”), which is incorporated herein by reference. 1.Grant of Stock Option. The Company grants to the Optionee on the date set forth above (the “Date of Grant”) an option (the “Stock Option”) to purchase, on the terms provided herein and in the Plan, up to the number of shares of Stock set forth above (the “Shares”) with an exercise price per Share as set forth above, in each case subject to adjustment pursuant to Section 7(b) of the Plan in respect of transactions occurring after the date hereof. 2.Meaning of Certain Terms. Except as otherwise defined herein, all capitalized terms used herein have the same meaning as in the

Name: Number of Restricted Stock Units subject to Award: Date of Grant:
Stock Unit Agreement • February 21st, 2024 • Ultragenyx Pharmaceutical Inc. • Pharmaceutical preparations

Ultragenyx Pharmaceutical Inc. 2023 Incentive PlanRestricted Stock Unit Agreement (Directors) This agreement (this “Agreement”) evidences an award (the “Award”) of restricted stock units (the “Restricted Stock Units”) granted by Ultragenyx Pharmaceutical Inc. (the “Company”) to the undersigned (the “Grantee”) pursuant to and subject to the terms of the Ultragenyx Pharmaceutical Inc. 2023 Incentive Plan (as amended from time to time, the “Plan”), which is incorporated herein by reference. 1. Grant of Restricted Stock Units. The Company grants to the Grantee on the date set forth above (the “Date of Grant”) an award consisting of the right to receive on the terms provided herein and in the Plan, one share of Stock with respect to each Restricted Stock Unit forming part of the Award, in each case, subject to adjustment pursuant to Section 7(b) of the Plan in respect of transactions occurring after the date hereof. 2. Meaning of Certain Terms. Except as otherwise defined herein, all capita

Commercial Supply Agreement Triheptanoin Ultrapure Between Ultragenyx Pharmaceutical Inc. (Herein known as UGX) And
Agreement • February 21st, 2024 • Ultragenyx Pharmaceutical Inc. • Pharmaceutical preparations

Whereas, UGX is a company engaged in the pharmaceutical field focusing on development of rare disease therapies and has obtained regulatory approval to market certain medicinal products based on active pharmaceutical ingredients;

ULTRAGENYX PHARMACEUTICAL INC. RESTRICTED STOCK UNIT AGREEMENT (EMPLOYEES)
Restricted Stock Unit Agreement • February 21st, 2024 • Ultragenyx Pharmaceutical Inc. • Pharmaceutical preparations

This agreement (this “Agreement”) evidences an award (the “Award”) of restricted stock units (the “Restricted Stock Units”) granted by Ultragenyx Pharmaceutical Inc. (the “Company”) to the undersigned (the “Grantee”) pursuant to and subject to the terms of the Ultragenyx Pharmaceutical Inc. 2023 Incentive Plan (as amended from time to time, the “Plan”), which is incorporated herein by reference.

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