0001016169-08-000026 Sample Contracts

SECOND AMENDMENT TO THE DEVELOPMENT AND LICENSE AGREEMENT
Development and License Agreement • May 15th, 2008 • Antares Pharma Inc • Surgical & medical instruments & apparatus

This Second Amendment to the Original Agreement (as defined below) (this “Amendment”) is entered into as of March 20, 2008 (the “Effective Date”), by and between ANTARES PHARMA, INC., a corporation incorporated in the State of Delaware, having a place of business located at Princeton Crossroads Corporate Center, 250 Phillips Boulevard, Suite 290, Ewing, New Jersey 08618 (formerly d/b/a a Minnesota corporation with a principal place of business in Exton, Pennsylvania) (“Antares”), and ELI LILLY AND COMPANY, a corporation incorporated in the State of Indiana, having a place of business at Lilly Corporate Center, Indianapolis, Indiana 46285 (“Lilly”). Antares and Lilly may be referred to herein individually as a “Party” and collectively as the “Parties.”

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