PROTHERICS PLC (F/K/A Proteus International PLC) AND THE BANK OF NEW YORK As Depositary AND OWNERS AND BENEFICIAL OWNERS OF AMERICAN DEPOSITARY RECEIPTS Deposit Agreement Dated as of June 20, 1995 Amended and Restated as of ________________, 2005Deposit Agreement • July 28th, 2005 • Protherics PLC • Pharmaceutical preparations • New York
