0001021408-03-005161 Sample Contracts

POYNER & SPRUILL L.L.P. DEFINED CONTRIBUTION PROTOTYPE PLAN AND TRUST
Trimeris Inc • March 27th, 2003 • Biological products, (no disgnostic substances)

Poyner & Spruill L.L.P., in its capacity as Prototype Plan Sponsor, establishes this Prototype Plan intended to conform to and qualify under §401 and §501 of the Internal Revenue Code of 1986, as amended. An Employer establishes a Plan and Trust under this Prototype Plan by executing an Adoption Agreement. If the Employer adopts this Plan as a restated Plan in substitution for, and in amendment of, an existing plan, the provisions of this Plan, as a restated Plan, apply solely to an Employee whose employment with the Employer terminates on or after the restated Effective Date of the Plan. If an Employee’s employment with the Employer terminates prior to the restated Effective Date, that Employee is entitled to benefits under the Plan as the Plan existed on the date of the Employee’s termination of employment.

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TRIMERIS, INC. EMPLOYEE 401(K) PLAN
Adoption Agreement • March 27th, 2003 • Trimeris Inc • Biological products, (no disgnostic substances)

The undersigned, Trimeris, Inc. (“Employer”), by executing this Adoption Agreement, elects to establish a retirement plan and trust (“Plan”) under the Poyner & Spruill LLP Defined Contribution Prototype Plan and Trust (basic plan document # 01). The Employer, subject to the Employer’s Adoption Agreement elections, adopts fully the Prototype Plan and Trust provisions. This Adoption Agreement, the basic plan document and any attached appendices or addenda, constitute the Employer’s entire plan and trust document. All section references within this Adoption Agreement are Adoption Agreement section references unless the Adoption Agreement or the context indicate otherwise. All article references are basic plan document and Adoption Agreement references as applicable. Numbers in parenthesis which follow headings are references to basic plan document sections. The Employer makes the following elections granted under the corresponding provisions of the basic plan document.

STATE OF NORTH CAROLINA
Lease Agreement • March 27th, 2003 • Trimeris Inc • Biological products, (no disgnostic substances)

THIS FOURTH AMENDMENT TO LEASE AGREEMENT (the “Fourth Amendment”), made and entered into as of the 28th day of January, 2003, by and between PHOENIX INVESTMENTS, LLC, a Virginia limited liability company (hereinafter called “Landlord”) [successor-in interest to Hamad Jassim Althani (“HJA”)], and TRIMERIS, INC., a Delaware corporation, (hereinafter called “Tenant”) as successor-in-interest to Blue Cross and Blue Shield of North Carolina (“BCBS”).

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