0001035704-03-000417 Sample Contracts

INTROGEN THERAPEUTICS, INC. WARRANT
Securities Agreement • June 19th, 2003 • Introgen Therapeutics Inc • Pharmaceutical preparations • Texas

Introgen Therapeutics, Inc., a Delaware corporation (the “Company”), hereby certifies that, for value received, [ ] or its registered assigns (the “Holder”), is entitled to purchase from the Company up to a total of [ ] shares of common stock, $0.001 par value per share (the “Common Stock”), of the Company (each such share, a “Warrant Share” and all such shares, the “Warrant Shares”) at an exercise price equal to $7.89 per share (as adjusted from time to time as provided in Section 8, the “Exercise Price”), at any time and from time to time from and after the date hereof and through and including June 18, 2008 (the “Expiration Date”), and subject to the following terms and conditions. This Warrant (this “Warrant”) is one of a series of similar warrants issued pursuant to that certain Securities Purchase Agreement dated as of the date hereof, by and among the Company and the Purchasers identified therein (the “Purchase Agreement”). All such warrants are referred to herein, collectively,

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SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • June 19th, 2003 • Introgen Therapeutics Inc • Pharmaceutical preparations • Texas

This Securities Purchase Agreement (this “Agreement”) is dated as of June 18, 2003 among Introgen Therapeutics, Inc., a Delaware corporation (the “Company”), and the purchasers identified on the signature pages hereto (each a “Purchaser” and collectively the “Purchasers”).

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