0001035704-04-000589 Sample Contracts

THIRD AMENDMENT TO LEASE
Lease • October 1st, 2004 • Myogen Inc • Pharmaceutical preparations

This Third Amendment to Lease Agreement (“Third Amendment”) is to be effective upon the closing of the Purchase and Sale Contract, Church Ranch Business Park, entered into by and between Scott Kaufman (“Landlord”) and LaSalle Bank, N.A., made and entered into effective as of July 30, 2004 (“Effective Date”) and is entered into by and between Landlord and Myogen, Inc. (“Tenant”). The Tenant and Landlord may be referred to herein as the “Parties” and either one of them may be referred to herein as a “Party”.

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SECOND AMENDMENT TO LEASE
Lease • October 1st, 2004 • Myogen Inc • Pharmaceutical preparations

This Second Amendment to Lease Agreement (“Second Amendment”) is to be effective April 15, 2004 (“Effective Date”), by and between LaSALLE BANK, N.A. (formerly known as LaSalle National Bank), as Trustee for the Certificateholders Under the Pooling and Servicing Agreement, dated as of November 27, 1998 “Landlord” and MYOGEN, INC., (“Tenant”). The Tenant and Landlord may be referred to herein as the “Parties” and either one of them may be referred to herein as a “Party.”

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