AMENDED AND RESTATED LICENSE AGREEMENT BY AND BETWEEN ORASENSE LTD A Bermuda Limited Company ISIS PHARMACEUTICALS, INC A Delaware Corporation AND ELAN CORPORATION, PLC A Public Irish Company October 24, 2002License Agreement • November 20th, 2002 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • New York
AMENDED AND RESTATED LICENSE AGREEMENT made this 24th day of October, 2002 among Elan Corporation, plc, Orasense Ltd. a Bermuda limited company, and Isis Pharmaceuticals, Inc., a Delaware corporation.
AMENDED AND RESTATED LICENSE AGREEMENT BY AND BETWEEN ORASENSE LTD A Bermuda Limited Company ISIS PHARMACEUTICALS, INC A Delaware Corporation AND ELAN CORPORATION, PLC A Public Irish Company October 24, 2002License Agreement • November 20th, 2002 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • New York
AMENDED AND RESTATED LICENSE AGREEMENT made this 24th day of October, 2002 among, Isis Pharmaceuticals, Inc., a Delaware corporation, Elan Corporation, plc, Orasense Ltd. a Bermuda limited company.
AMENDED AND RESTATED SUBSCRIPTION, JOINT DEVELOPMENT AND OPERATING AGREEMENT ELAN CORPORATION, PLC ELAN INTERNATIONAL SERVICES, LTD. ISIS PHARMACEUTICALS, INC. AND ORASENSE LTD. October 24, 2002Subscription, Joint Development and Operating Agreement • November 20th, 2002 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • New York
The Shares will be issued under an exemption or exemptions from registration under the Securities Act. Accordingly, the certificates evidencing the Shares shall, upon issuance, contain the following legend:
INDEXTermination Agreement • November 20th, 2002 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • New York
IN CONSIDERATION OF THE MUTUAL COVENANTS CONTAINED HEREIN, AND OTHER GOOD AND VALUABLE CONSIDERATION, THE RECEIPT AND ADEQUACY OF WHICH ARE HEREBY ACKNOWLEDGED, IT IS HEREBY AGREED AS FOLLOWS:
