0001047469-03-024415 Sample Contracts

METABASIS THERAPEUTICS, INC. AMENDED AND RESTATED INVESTORS' RIGHTS AGREEMENT
Investors' Rights Agreement • July 17th, 2003 • Sicor Inc • Pharmaceutical preparations • California

This Amended and Restated Investors' Rights Agreement is made as of July 18, 2000 (the "Effective Date") by and among Metabasis Therapeutics, Inc., a Delaware corporation (the "Company") and the investors listed on Exhibit A hereto, including, without limitation, SICOR Inc., a Delaware corporation ("SICOR"), and Sankyo Company, Ltd., a Japanese corporation ("Sankyo"), each of which is herein referred to as an "Investor."

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