0001047469-05-009447 Sample Contracts

CONSULTING AGREEMENT
Consulting Agreement • April 7th, 2005 • Gentium S.p.A. • Pharmaceutical preparations

This Consulting Agreement ("Agreement") is by and between KKS-UKT, gGmbH, a German Corporation ("KKS"), located at Otfried-Müller-Str. 45, 72076 Tübingen, Germany, and Gentium, an Italy Corporation ("Gentium"), located at Piazza XX Settembre 2, Villa Gardia (Como), Italy.

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GENERAL CONSULTING AGREEMENT
Consulting Agreement • April 7th, 2005 • Gentium S.p.A. • Pharmaceutical preparations • New Jersey

This Consulting Agreement ("Agreement") is by and between Bradstreet Clinical Research & Associates, Inc., a New Jersey Corporation ("Bradstreet"), located at 1588 Route 130 North, Suite C-2, North Brunswick, NJ, 08902, and Gentium, an Italy Corporation ("Gentium"), located at Piazza XX Settembre, 2, 22079 Villa Guardia (CO), Italy, Villa Gardia (Como), Italy.

INVESTORS' RIGHTS AGREEMENT
Investors' Rights Agreement • April 7th, 2005 • Gentium S.p.A. • Pharmaceutical preparations • New York

THIS INVESTORS' RIGHTS AGREEMENT is made as of the 4th day of April, 2005, by and between Gentium S.p.A., a joint stock company (società per azioni) incorporated and organized under the laws of the Republic of Italy (the "Company"), on the one hand, and Sigma Tau Finanziaria S.p.A., a corporation incorporated under the laws of Italy ("Sigma Tau"), on the other hand.

SUBSCRIPTION AGREEMENT
Subscription Agreement • April 7th, 2005 • Gentium S.p.A. • Pharmaceutical preparations • New York

SUBSCRIPTION AGREEMENT (this "Agreement") made as of the date set forth on the signature page hereof between Gentium S.p.A., a joint stock company (societá per azioni) incorporated and organized under the laws of the Republic of Italy having a place of business at Piazza XX Settembre, n. 2, 22079 Villa Guardia, Como, Italy (the "Company"), and the undersigned (the "Subscriber").

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