3,500,000 Shares Osiris Therapeutics, Inc. Common Stock ($0.001 Par Value) EQUITY UNDERWRITING AGREEMENTEquity Underwriting Agreement • August 3rd, 2006 • Osiris Therapeutics, Inc. • Biological products, (no disgnostic substances) • New York
Osiris Therapeutics, Inc., a Delaware corporation (the “Company”), proposes to sell to the several underwriters (the “Underwriters”) named in Schedule I hereto for whom you are acting as Representatives (the “Representatives”) an aggregate of 3,500,000 shares (the “Firm Shares”) of the Company’s common stock, $0.001 par value (the “Common Stock”). The respective amounts of the Firm Shares to be so purchased by the several Underwriters are set forth opposite their names in Schedule I hereto. The Company also proposes to sell at the Underwriters’ option an aggregate of up to 525,000 additional shares of the Company’s Common Stock (the “Option Shares”) as set forth below.
