0001047469-06-013777 Sample Contracts

],000,000 [ ]% Convertible Senior Notes due November 15, 2011
Indenture • November 9th, 2006 • Millennium Pharmaceuticals Inc • Pharmaceutical preparations • New York

INDENTURE, dated as of November [ ], 2006, between Millennium Pharmaceuticals, Inc., a Delaware corporation (as the "Company") and U.S. Bank National Association, a national banking association, as Trustee.

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Standard Contracts

MILLENNIUM PHARMACEUTICALS, INC. [ ]% CONVERTIBLE SENIOR NOTES DUE 2011 UNDERWRITING AGREEMENT
Underwriting Agreement • November 9th, 2006 • Millennium Pharmaceuticals Inc • Pharmaceutical preparations • New York

Letter Agreement, dated March 4, 2005, relating to the License, Development and Commercialization Agreement by and between GlaxoSmithKline plc and the Company, dated June 22, 2004.

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