0001047469-08-002053 Sample Contracts

Distribution and Development Agreement for Ciclesonide in the USA By and between Nycomed GmbH (formerly known as ALTANA Pharma AG) Byk Gulden-Strasse 2 78467 Konstanz Federal Republic of Germany and Sepracor Inc. 84 Waterford Drive Marlborough, MA...
Sepracor Inc /De/ • February 29th, 2008 • Pharmaceutical preparations

This Distribution and Development Agreement relating to the pharmaceutical compound ciclesonide, dated this January 25th, 2008 is being entered into by and between Nycomed GmbH (formerly known as ALTANA Pharma AG), a corporation organized and existing under the laws of Germany and having its principal office at Byk-Gulden-Strasse 2, 78467 Konstanz, Federal Republic of Germany ("Nycomed"), and Sepracor Inc., a corporation organized and existing under the laws of the state of Delaware and having its principal office at 84 Waterford Drive, Marlborough, MA 01752, USA ("Sepracor"). Each or both of Nycomed and Sepracor are hereinafter referred to as "Party" or "Parties", as intended in the given context.

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Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions. LICENSE AGREEMENT
License Agreement • February 29th, 2008 • Sepracor Inc /De/ • Pharmaceutical preparations • New York

THIS LICENSE AGREEMENT (this "Agreement") is made and entered into as of December 31, 2007 (the "Effective Date") by and between BIAL—PORTELA & Ca, S.A., a Portuguese corporation having a principal place of business at À Av. da Siderurgia Nacional, 4745-457 S. Mamede do Coronado, Portugal (hereinafter referred to as "BIAL") and SEPRACOR INC., a Delaware corporation having a principal place of business at 84 Waterford Drive, Marlborough, MA 01752, USA (hereinafter referred to as "SEPRACOR").

Amended and Restated Manufacturing Services Agreement Among Patheon Inc., Patheon Pharmaceuticals Inc. & MOVA Pharmaceutical Corporation and Sepracor Inc. November 6, 2007
Quality Agreement • February 29th, 2008 • Sepracor Inc /De/ • Pharmaceutical preparations • Delaware

PATHEON INC., a corporation existing under the laws of Canada ("Patheon Inc."), PATHEON PHARMACEUTICALS INC., a corporation existing under the laws of Delaware ("PPI"), and MOVA PHARMACEUTICAL CORPORATION, a corporation existing under the laws of the Commonwealth of Puerto Rico ("MOVA"),

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