0001047469-08-002233 Sample Contracts

ASSET PURCHASE AGREEMENT dated as of December 18, 2007 by and between Siegfried Ltd. (as "Seller") and Arena Pharmaceuticals GmbH (as "Buyer")
Asset Purchase Agreement • March 5th, 2008 • Arena Pharmaceuticals Inc • Pharmaceutical preparations

THIS ASSET PURCHASE AGREEMENT (this "Agreement"), dated as of December 18, 2007 (the "Effective Date"), is entered into by and between Siegfried Ltd., a company organized under the laws of Switzerland with registered office at Untere Brühlstrasse 4, 4800 Zofingen, Switzerland ("Seller"), and Arena Pharmaceuticals GmbH, a company organized under the laws of Switzerland with its registered office at c/o Siegfried Holding AG, Untere Brühlstrasse 4, 4800 Zofingen, Switzerland ("Buyer"). Seller and Buyer sometimes are referred to herein collectively as the "Parties" and individually as a "Party".

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TOLL MANUFACTURING AGREEMENT
Toll Manufacturing Agreement • March 5th, 2008 • Arena Pharmaceuticals Inc • Pharmaceutical preparations

WHEREAS, SIEGFRIED wishes to purchase from ARENA bulk tablets/capsules and packaged tablets/capsules for commercial sale by SIEGFRIED or SIEGFRIED’s partners.

SECOND AMENDMENT TO RESEARCH COLLABORATION AND LICENSE AGREEMENT
Research Collaboration and License Agreement • March 5th, 2008 • Arena Pharmaceuticals Inc • Pharmaceutical preparations

This SECOND AMENDMENT TO RESEARCH COLLABORATION AND LICENSE AGREEMENT (this “Second Amendment”) dated as of February 20, 2007, is entered into by and between Merck & Co., Inc. (“MERCK”) and ARENA PHARMACEUTICALS, INC., (“ARENA”) and amends that certain Research Collaboration and License Agreement between MERCK and ARENA, effective as of October 21, 2002, as subsequently amended by the First Amendment to the Research Collaboration and License Agreement between MERCK and ARENA, dated October 20, 2004 (as so amended, the “Agreement”).

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