0001047469-08-002693 Sample Contracts

RESEARCH AGREEMENT
Research Agreement • March 13th, 2008 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • New York

THIS RESEARCH AGREEMENT (this "Agreement"), dated as of October 22, 2007 (the "Effective Date"), is entered into by and between Isis Pharmaceuticals, Inc., a Delaware corporation ("Isis"), and CHDI, Inc., a New Jersey corporation (the "Foundation"). Isis and the Foundation will hereinafter be referred to individually as a "Party" and collectively as the "Parties".

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