0001047469-08-012090 Sample Contracts

SECOND AMENDMENT TO LEASE
Synta Pharmaceuticals Corp • November 13th, 2008 • Pharmaceutical preparations

SECOND AMENDMENT TO LEASE dated as of this 22 day of August, 2008 by and between MORTIMER B. ZUCKERMAN AND EDWARD H. LINDE, Trustees of 91 Hartwell Avenue Trust under Declaration of Trust dated September 28, 1981 filed with the Middlesex South Registry as Document No. 616455 as amended by instruments dated December 10, 1984 and April 17, 1991 respectively filed with said Registry District as Document Nos. 675674 and 844541 but not individually ("Landlord") and SYNTA PHARMACEUTICALS, INC., a Delaware corporation ("Tenant").

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SEVERANCE AND CHANGE OF CONTROL AGREEMENT
Severance and Change of Control Agreement • November 13th, 2008 • Synta Pharmaceuticals Corp • Pharmaceutical preparations • Massachusetts

This Agreement (the "Agreement") is entered into as of the 6th day of August, 2008 by and between Synta Pharmaceuticals Corp., a Delaware corporation (the "Company"), and Michael Bailey (the "Executive").

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