0001047469-10-010575 Sample Contracts

STANDARD FORM MULTI-TENANT NET LEASE (Non-California)
Lease • December 23rd, 2010 • Supernus Pharmaceuticals Inc

THIS LEASE (this “Lease”) is made as of April 19, 1999 (“Effective Date”), by and between ARE ACQUISITIONS, LLC, a Delaware limited liability company (“Landlord”) and SHIRE LABORATORIES INC., a Delaware corporation (“Tenant”).

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INVESTOR RIGHTS AGREEMENT
Investor Rights Agreement • December 23rd, 2010 • Supernus Pharmaceuticals Inc • Delaware

INVESTOR RIGHTS AGREEMENT (the “Agreement”) is entered into as of the 22nd day of December 2005, by and among Supernus Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and the holders of shares of Series A Convertible Preferred Stock, par value $0.001 per share (the “Series A Preferred Stock”) listed on the Schedule of Investors annexed hereto and each person who shall, after the date hereof, acquire shares of Series A Preferred Stock and join in and become a party to this Agreement by executing and delivering to the Company an Instrument of Accession in the form of Schedule I hereto (collectively the “Investors”).

SUPERNUS PHARMACEUTICALS, INC. STOCK RESTRICTION AGREEMENT
Stock Restriction Agreement • December 23rd, 2010 • Supernus Pharmaceuticals Inc • Delaware

THIS STOCK RESTRICTION AGREEMENT (the “Agreement”) is made as of the 22nd day of December 22„ 2005 (the “Effective Date”), by and between Supernus Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and Jack Khattar (the “Stockholder”).

EMPLOYMENT AGREEMENT
Employment Agreement • December 23rd, 2010 • Supernus Pharmaceuticals Inc • Maryland

This AGREEMENT (the “Agreement”) is made as of December 22, 2005 (the “Effective Date”), by and between Supernus Pharmaceuticals, Inc., a Delaware corporation (the “Employer”), and Jack Khattar (the “Executive”). In consideration of the mutual covenants contained in this Agreement, the Employer and the Executive agree as follows:

THIRD AMENDMENT TO LEASE
Lease • December 23rd, 2010 • Supernus Pharmaceuticals Inc

This Third Amendment (the “Amendment”) to Lease is made as of November 24, 2010, by and between ARE-EAST GUDE LEASE, LLC, a Delaware limited liability company (“Landlord”), successor-in-interest to ARE ACQUISITIONS, LLC, a Delaware limited liability company (“Original Landlord”), and SUPERNUS PHARMACEUTICALS, INC., a Maryland corporation (“Tenant”) successor-in-interest to SHIRE LABORATORIES INC., a Delaware corporation (“Original Tenant”).

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