0001047469-12-002631 Sample Contracts

SETTLEMENT AND LICENSE AGREEMENT
Settlement and License Agreement • March 14th, 2012 • Affymax Inc • Pharmaceutical preparations • New York

This SETTLEMENT AND LICENSE AGREEMENT (this “Agreement”) is entered into effective as of the November 7, 2011 (the “Effective Date”) by Affymax, Inc. (“Affymax”) and Janssen Biotech, Inc. (formerly known as Centocor Ortho Biotech Inc., “Ortho”) (each of Ortho and Affymax, a “Party” and together the “Parties”).

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THIRD AMENDMENT TO COLLABORATION AND LICENSE AGREEMENTS
Collaboration and License Agreement • March 14th, 2012 • Affymax Inc • Pharmaceutical preparations

This Amendment to Collaboration and License Agreements (the “Amendment”) is entered into on November 7, 2011 (the “Amendment Effective Date”) between AFFYMAX, INC., a Delaware corporation, with its principal place of business at 4001 Miranda Avenue, Palo Alto, CA 94304, U.S.A. (“Affymax”), and TAKEDA PHARMACEUTICAL COMPANY LIMITED, a company incorporated under the laws of Japan, with its principal place of business at 1-1, Doshomachi 4-chome, Chuo-ku, Osaka, 540-8645, Japan (“Takeda”).

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