0001047469-13-007502 Sample Contracts

FORM OF INDEMNIFICATION AGREEMENT
Indemnification Agreement • July 11th, 2013 • Onconova Therapeutics, Inc. • Pharmaceutical preparations • Delaware

This Indemnification Agreement (the “Agreement”) is made and entered into this [·] day of [·], 2013, by and between Onconova Therapeutics, Inc., a Delaware corporation (the “Company,” which term shall include, where appropriate, any Entity (as hereinafter defined) controlled directly or indirectly by the Company), and [·] (the “Indemnitee”).

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EIGHTH AMENDED AND RESTATED STOCKHOLDERS’ AGREEMENT
Stockholders Agreement • July 11th, 2013 • Onconova Therapeutics, Inc. • Pharmaceutical preparations • Delaware

THIS EIGHTH AMENDED AND RESTATED STOCKHOLDERS’ AGREEMENT (this “Agreement”) made as of July 27, 2012, by and among Onconova Therapeutics, Inc., a Delaware corporation (the “Corporation”), the persons listed as owners of Series A Preferred Stock on Schedule I hereto (the “Series A Investors”), the persons listed as owners of Series B Preferred Stock on Schedule I hereto (the “Series B Investors”), the persons listed as owners of Series C Preferred Stock on Schedule I hereto (the “Series C Investors”), the persons listed as owners of Series D Preferred Stock on Schedule I hereto (the “Series D Investors”), the persons listed as owners of Series E Preferred Stock on Schedule I hereto (the “Series E Investors”), the persons listed as owners of Series F Preferred Stock on Schedule I hereto (the “Series F Investors”), the persons listed as owners of Series G Preferred Stock and/or Warrants to purchase Series G Preferred Stock (the “Series G Warrants”) on Schedule I hereto (the “Series G Inve

AMENDMENT NO. 1 TO EIGHTH AMENDED AND RESTATED STOCKHOLDERS’ AGREEMENT Dated as of July 9, 2013
Stockholders’ Agreement • July 11th, 2013 • Onconova Therapeutics, Inc. • Pharmaceutical preparations • Delaware

Reference is made to that certain Eighth Amended and Restated Stockholders’ Agreement, dated July 27, 2012 (the “Stockholders’ Agreement”), by and among Onconova Therapeutics, Inc., a Delaware corporation (the “Corporation”) and the Stockholders (as that term is defined in the Stockholders’ Agreement). All capitalized terms used and not otherwise defined herein have the respective meanings given to them in the Stockholders’ Agreement.

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