0001047469-14-001578 Sample Contracts

CONFIDENTIAL PORTIONS OF THIS AGREEMENT HAVE BEEN OMITTED AND FILED SEPARATELY WITH THE COMMISSION. CONFIDENTIAL TREATMENT HAS BEEN REQUESTED FOR SUCH PORTIONS. ASTERISKS DENOTE OMISSIONS. ADDENDUM TO LICENSE AGREEMENT
License Agreement • February 28th, 2014 • Exact Sciences Corp • Services-commercial physical & biological research

This is an Addendum to the License Agreement dated July 26, 2010 (the “Agreement”) by and between MDxHealth S.A. (“MDxH” formerly OncoMethylome Sciences, S.A. or “Onco”) and Exact Sciences Corporation (“Exact”). The terms of this Addendum shall take precedence over, and shall supersede any conflicting terms contained in, the Agreement. Any terms which are defined in the Agreement shall have the same meaning in this Addendum, unless otherwise defined herein; provided further that all references to “Onco” in the Agreement shall be deemed to be replaced with “MDxH”. The effective date of this Addendum is May 6, 2011.

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CONFIDENTIAL PORTIONS OF THIS AGREEMENT HAVE BEEN OMITTED AND FILED SEPARATELY WITH THE COMMISSION. CONFIDENTIAL TREATMENT HAS BEEN REQUESTED FOR SUCH PORTIONS. ASTERISKS DENOTE OMISSIONS. LICENSE AGREEMENT
License Agreement • February 28th, 2014 • Exact Sciences Corp • Services-commercial physical & biological research • New York

This License Agreement (“Agreement”) made this 26th day of July, 2010 (the “Effective Date”), by and between Oncomethylome Sciences, S.A. (“Onco”), having its principal office at Tour 5 GIGA niveau +3, Av. de I’Hopital 11, 4000 Liege, Belgium, and Exact Sciences Corporation (“Exact”), having its principal place of business at 441 Charmany Drive, Madison, WI 53719.

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