0001047469-16-017053 Sample Contracts

TiGenix [ ]American Depositary Shares (each representing Twenty (20) Ordinary Shares) (with no nominal value) UNDERWRITING AGREEMENT
Underwriting Agreement • December 5th, 2016 • TiGenix NV • Pharmaceutical preparations • New York

TiGenix, a limited liability company (naamloze vennootschap) organized and existing under the laws of the Kingdom of Belgium (“Belgium”) with registered office at Romeinse straat 12 box 2, 3001 Leuven, Belgium and registered with the Crossroads Bank for Enterprises under the number 0471.340.123 (Register of Legal Entities of Leuven) (the “Company”), proposes to issue to the several underwriters (the “Underwriters”) named in Schedule I hereto for whom you are acting as representatives (the “Representatives”) an aggregate of [ ] ordinary shares, with no nominal value, of the Company (the “Ordinary Shares” and each an “Ordinary Share”) in the form of [ ] American Depositary Shares (“ADSs”), through a public offering in the United States (the “Firm ADSs”).

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