0001047469-17-000163 Sample Contracts

LOAN AND SECURITY AGREEMENT
Loan and Security Agreement • January 12th, 2017 • Strongbridge Biopharma PLC • Pharmaceutical preparations

THIS LOAN AND SECURITY AGREEMENT (as the same may from time to time be amended, modified, supplemented or restated, this “Agreement”) dated as of December 28, 2016 (the “Effective Date”) among OXFORD FINANCE LLC, a Delaware limited liability company with an office located at 133 North Fairfax Street, Alexandria, Virginia 22314 (“Oxford”), as collateral agent (in such capacity, “Collateral Agent”), the Lenders listed on Schedule 1.1 hereof or otherwise a party hereto from time to time including Oxford in its capacity as a Lender and HORIZON TECHNOLOGY FINANCE CORPORATION, a Delaware corporation with an office located at 312 Farmington Avenue, Farmington, Connecticut 06032 (“Horizon”) (each a “Lender” and collectively, the “Lenders”), and STRONGBRIDGE BIOPHARMA PUBLIC LIMITED COMPANY, a public limited company incorporated under the laws of Ireland with company number 562659 and having its registered office at Arthur Cox Building, Earlsfort Terrace, Dublin 2, Ireland (“Irish Borrower”), C

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ASSET PURCHASE AGREEMENT between TARO PHARMACEUTICALS NORTH AMERICA, INC. and STRONGBRIDGE BIOPHARMACEUTICALS PLC Dated December 12, 2016
Asset Purchase Agreement • January 12th, 2017 • Strongbridge Biopharma PLC • Pharmaceutical preparations • New York

This Asset Purchase Agreement dated December 12 2016, is by and between Taro Pharmaceuticals North America, Inc., a Cayman Islands limited company, with a place of business at Harbour Place, 103 South Church Street, Grand Cayman KY1-1202, Cayman Islands (“Taro”) and Strongbridge Biopharmaceuticals plc, a company organized under the laws of Ireland, having its Company’s registered office at Arthur Cox Building, Earlsfort Terrace, Dublin 2, Ireland and having its principal U.S. place of business at 900 Northbrook Drive, Suite 200, Trevose, PA 19053 (“Strongbridge”).

SUPPLY AGREEMENT between TARO PHARMACEUTICALS NORTH AMERICA, INC. and STRONGBRIDGE BIOPHARMACEUTICALS PLC Effective as of December 12, 2016
Supply Agreement • January 12th, 2017 • Strongbridge Biopharma PLC • Pharmaceutical preparations • New York

This Supply Agreement dated as of December 12, 2016 (the “Effective Date”), is by and between Taro Pharmaceuticals North America, Inc. a company organized under the laws of the country of Cayman Islands with a place of business at Harbour Place, 103 South Church Street, Grand Cayman KY1-1202, Cayman Islands (“Seller”) and Strongbridge Biopharmaceuticals plc, a company organized under the laws of Ireland, having its Company’s registered office at Arthur Cox Building, Earlsfort Terrace, Dublin 2, Ireland and having its principal U.S. place of business at 900 Northbrook Drive, Suite 200, Trevose, PA 19053 (“Buyer”). Buyer and Seller are sometimes collectively referred to herein as the “Parties” and separately as a “Party.”

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