0001047469-17-007269 Sample Contracts

REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • November 22nd, 2017 • CollPlant Holdings Ltd. • Orthopedic, prosthetic & surgical appliances & supplies

This Registration Rights Agreement (this “Agreement”) is made and entered into as of , 2017, between CollPlant Holdings Ltd., a company organized under the laws of the State of Israel (the “Company”), and each of the several purchasers signatory hereto (each such purchaser, a “Purchaser” and, collectively, the “Purchasers”).

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WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES COLLPLANT HOLDINGS LTD.
Security Agreement • November 22nd, 2017 • CollPlant Holdings Ltd. • Orthopedic, prosthetic & surgical appliances & supplies

THIS WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES (the “Warrant”) certifies that, for value received, Meitav Dash Provident Funds And Pension Ltd., or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date hereof (the “Initial Exercise Date”) and on or prior to the close of business at 5:00 p.m. (New York City time) on the five (5) year anniversary of the Initial Exercise Date (the “Termination Date) but not thereafter, to subscribe for and purchase from CollPlant Holdings Ltd., a company organized under the laws of the State of Israel (the “Company”), up to Ordinary Shares (the “Warrant Shares”) represented by 50 American Depositary Shares (“ADSs”), as subject to adjustment hereunder (the “Warrant ADSs”). The purchase price of one Warrant Share under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b). Notwiths

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • November 22nd, 2017 • CollPlant Holdings Ltd. • Orthopedic, prosthetic & surgical appliances & supplies

This Securities Purchase Agreement (this “Agreement”) is dated as of November 9, 2017, between CollPlant Holdings Ltd., a company organized under the laws of the State of Israel (the “Company”), and Ami Sagi, an Israeli citizen (including his successors and assigns, the “Purchaser”).

Waiver
Waiver • November 22nd, 2017 • CollPlant Holdings Ltd. • Orthopedic, prosthetic & surgical appliances & supplies

This waiver is made in connection with the Agreement, dated July 13, 2004 by and among Meitav Technological Enterprises Initiation Center Ltd., Yehuda Zafrir Feidin, Yissum- the Company for the Development of Research of the Hebrew University of Jerusalem (“Yissum”) and Professor Oded Shoseyov (the “Agreement”):

WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES COLLPLANT HOLDINGS LTD.
Security Agreement • November 22nd, 2017 • CollPlant Holdings Ltd. • Orthopedic, prosthetic & surgical appliances & supplies

THIS WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES (the “Warrant”) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date hereof (the “Initial Exercise Date”) and on or prior to the close of business at 5:00 p.m. (New York City time) on the five (5) year anniversary of the Initial Exercise Date (the “Termination Date) but not thereafter, to subscribe for and purchase from CollPlant Holdings Ltd., a company organized under the laws of the State of Israel (the “Company”), up to 49,607,407 Ordinary Shares (the “Warrant Shares”) represented by American Depositary Shares (“ADSs”), as subject to adjustment hereunder (the “Warrant ADSs”). The purchase price of one Warrant Share under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b). Notwithstanding anything herein to the contrar

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • November 22nd, 2017 • CollPlant Holdings Ltd. • Orthopedic, prosthetic & surgical appliances & supplies • New York

This Securities Purchase Agreement (this “Agreement”) is dated as of September 6, 2017, between CollPlant Holdings Ltd., a company organized under the laws of the State of Israel (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively, the “Purchasers”).

PRE-PAID WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES COLLPLANT HOLDINGS LTD.
Security Agreement • November 22nd, 2017 • CollPlant Holdings Ltd. • Orthopedic, prosthetic & surgical appliances & supplies

THIS PRE-PAID WARRANT TO PURCHASE ORDINARY SHARES REPRESENTED BY AMERICAN DEPOSITARY SHARES (the “Warrant”) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date hereof (the “Initial Exercise Date”) until such date that this Warrant is exercised in full, to subscribe for and purchase from CollPlant Holdings Ltd., a company organized under the laws of the State of Israel (the “Company”), up to Ordinary Shares (the “Warrant Shares”) represented by American Depositary Shares (“ADSs”), as subject to adjustment hereunder (the “Warrant ADSs”). Notwithstanding anything herein to the contrary, in lieu of receiving ADS Warrant Shares, the Holder may choose to receive ordinary shares and for such purposes ADS “Warrant Shares” shall be deemed ordinary shares, taking into consideration the applicable ratio and necessary adjustments to the num

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