0001047469-18-006516 Sample Contracts

SHARES OF COMMON STOCK AND WARRANTS (EXERCISABLE FOR SHARES) OF JAGUAR HEALTH, INC. UNDERWRITING AGREEMENT
Underwriting Agreement • October 1st, 2018 • Jaguar Health, Inc. • Pharmaceutical preparations • New York

The undersigned, Jaguar Health, Inc., a company incorporated under the laws of Delaware (collectively with its subsidiaries and affiliates, including, without limitation, all entities disclosed or described in the Registration Statement as being subsidiaries or affiliates of Jaguar Health, Inc., the “Company”), hereby confirms its agreement (this “Agreement”) with the several underwriters (such underwriters, including the Representative (as defined below), the “Underwriters” and each an “Underwriter”) named in Schedule I hereto for which H.C. Wainwright & Co., LLC is acting as representative to the several Underwriters (the “Representative” and if there are no Underwriters other than the Representative, references to multiple Underwriters shall be disregarded and the term Representative as used herein shall have the same meaning as Underwriter) on the terms and conditions set forth herein.

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