ADAGENE INC. ORDINARY SHARES, PAR VALUE US$0.0001 PER SHARE in the Form of American Depositary Shares UNDERWRITING AGREEMENTUnderwriting Agreement • February 5th, 2021 • Adagene Inc. • Pharmaceutical preparations • New York
The undersigned understands that Goldman Sachs (Asia) L.L.C., Morgan Stanley & Co. LLC and Jefferies LLC, as representatives (each, a “Representative,” and collectively, the “Representatives”) of the several underwriters (the “Underwriters”), propose to enter into an Underwriting Agreement (the “Underwriting Agreement”) with Adagene Inc., an exempted company incorporated with limited liability under the laws of the Cayman Islands (the “Company”), providing for the public offering (the “Public Offering”) by the several Underwriters, including the Representatives, of a certain number of American Depositary Shares (“American Depositary Shares”), representing ordinary shares, par value US$0.0001 per share, of the Company (the “Ordinary Shares”). The undersigned is, or is expected to be, a record or beneficial owner of American Depositary Shares, Ordinary Shares, or securities convertible into or exercisable or exchangeable for such American Depositary Shares or Ordinary Shares (collectivel
