0001062822-09-000118 Sample Contracts

AMENDMENT TO SECURITIES PURCHASE AGREEMENT

Securities Purchase Agreement • October 7th, 2009 • Lexicon Pharmaceuticals, Inc./De • Pharmaceutical preparations • New York

• Contract Type
  Securities Purchase Agreement
• Filed
  October 7th, 2009
• Company
  Lexicon Pharmaceuticals, Inc./De
• Industry
  Pharmaceutical preparations
• Jurisdiction
  New York

This Amendment to Securities Purchase Agreement (this “Amendment”) is entered into as of October 7, 2009 by and between Invus, L.P., a Bermuda limited partnership (the “Investor”), and Lexicon Pharmaceuticals, Inc., a Delaware corporation (the “Company”). Capitalized terms used but not otherwise defined herein shall have the meanings ascribed to them in the Securities Purchase Agreement (as defined below).