0001062993-07-003809 Sample Contracts

Contract
Subscription Agreement • October 1st, 2007 • Upstream Biosciences Inc. • In vitro & in vivo diagnostic substances • British Columbia

THIS PRIVATE PLACEMENT SUBSCRIPTION AGREEMENT RELATES TO AN OFFERING OF SECURITIES IN AN OFFSHORE TRANSACTION TO PERSONS WHO ARE NOT U.S. PERSONS (AS DEFINED HEREIN) PURSUANT TO REGULATION S UNDER THE UNITED STATES SECURITIES ACT OF 1933, AS AMENDED (THE "1933 ACT").

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STOCK OPTION AND SUBSCRIPTION AGREEMENT U.S. Persons
Option and Subscription Agreement • October 1st, 2007 • Upstream Biosciences Inc. • In vitro & in vivo diagnostic substances • British Columbia

NOW THEREFORE THIS AGREEMENT WITNESSES that in consideration of the covenants and agreements set forth herein and for other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the parties hereto agree as follows:

Sample 1
STOCK OPTION AND SUBSCRIPTION AGREEMENT For U.S. Persons
Subscription Agreement • October 1st, 2007 • Upstream Biosciences Inc. • In vitro & in vivo diagnostic substances • British Columbia

NOW THEREFORE THIS AGREEMENT WITNESSES that in consideration of the covenants and agreements set forth herein and for other good and valuable consideration, the receipt and sufficiency whereof is hereby acknowledged, the parties hereto agree as follows:

Sample 1
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