0001062993-08-005130 Sample Contracts

MEDICURE INC. and COMPUTERSHARE TRUST COMPANY OF CANADA as Rights Agent SHAREHOLDER RIGHTS PLAN AGREEMENT Dated as of August 25, 2005, as amended October 29, 2008
Shareholder Rights Plan Agreement • November 20th, 2008 • Medicure Inc • Pharmaceutical preparations • Ontario

THIS AGREEMENT dated as of the 25th day of August, 2005, as amended on the 29th day of October, 2008 between Medicure Inc. (the “Corporation”), a corporation incorporated under the Canada Business Corporations Act, and Computershare Trust Company of Canada, a trust company incorporated under the laws of Canada, as Rights Agent (the “Rights Agent”), which term shall include any successor Rights Agent hereunder.

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