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0001070081-20-000064 Sample Contracts

Certain identified information has been marked in the exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. FIRST AMENDMENT TO LEASE AGREEMENT
Lease Agreement • March 2nd, 2020 • PTC Therapeutics, Inc. • Pharmaceutical preparations

This First Amendment (“First Amendment”) to the Lease Agreement ( “Lease”) is made on this 7th day of October 2019 by and between BRISTOL-MYERS SQUIBB COMPANY, a Delaware corporation, having an office at 3551 Lawrenceville Princeton Road, Princeton, New Jersey 08540 (“Landlord”), and PTC THERAPEUTICS, INC., a Delaware Corporation, having an office at 100 Corporate Court, South Plainfield, NJ 07080-2449 (“Tenant”).

Standard Contracts

License and Technology Transfer Agreement Amendment No. 2 (“Amendment No. 2”) Effective Date: Dec. 1, 2019
License and Technology Transfer Agreement • March 2nd, 2020 • PTC Therapeutics, Inc. • Pharmaceutical preparations

WHEREAS, Party A and Party B entered in to a certain License and Technology Transfer Agreement with Agilis BioTherapeutics, LLC, NTU Contract No.: 104-I0TC-10, dated December 23, 2015 (the “Agreement”);