0001104659-03-005131 Sample Contracts

Amendment No. 4 to Research, License and Royalty Agreement
Research, License and Royalty Agreement • March 27th, 2003 • Pharmacopeia Inc • Services-commercial physical & biological research • Delaware

This Amendment No. 4 to Research, License and Royalty Agreement (the “Amendment”) is entered into on July 22, 1998 by and between Pharmacopeia, Inc. (“Pharmacopeia”) and Berlex Laboratories, Inc. (“Berlex”), effective as of February 15, 1998 (the “Amendment Effective Date”), and amends that certain Research, License and Royalty Agreement entered into by Pharmacopeia and Berlex effective as of February 15, 1995 (the “Agreement”), as amended by Amendment No. 1 to Research, License and Royalty Agreement effective as of November 27, 1996, Amendment No. 2 to Research, License and Royalty Agreement effective as of June 30, 1997, and Amendment No. 3 to Research License and Royalty Agreement effective as of November 21, 1997.

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EMPLOYMENT AGREEMENT OF MARK J. EMKJER
Employment Agreement • March 27th, 2003 • Pharmacopeia Inc • Services-commercial physical & biological research • New Jersey

This EMPLOYMENT AGREEMENT (the “Agreement”) is made and entered into as of the 3rd day of December, 2002, by and between PHARMACOPEIA, INC., a Delaware corporation (hereinafter, the “Company”), and Mark J. Emkjer, an individual (hereinafter, “Employee”).

Contract
Research, License and Royalty Agreement • March 27th, 2003 • Pharmacopeia Inc • Services-commercial physical & biological research

This Amendment No. 5 to the Research, License and Royalty Agreement (the “Amendment”) is entered into by and between Pharmacopeia, Inc. (“Pharmacopeia”) and Berlex Laboratories, Inc. (“Berlex”), and amends the Research, License and Royalty Agreement between Berlex and Pharmacopeia dated February 15, 1995 (“the 1995 Agreement”), as previously amended in Amendment Nos. 1 through 4.

SEPARATION AGREEMENT AND RELEASE OF CLAIMS
Separation Agreement • March 27th, 2003 • Pharmacopeia Inc • Services-commercial physical & biological research • New Jersey

This SEPARATION AGREEMENT AND RELEASE OF CLAIMS (the “Agreement”) is entered into as of the 30th day of September, 2002, by and between PHARMACOPEIA, INC., a Delaware corporation (the “Company”), and MICHAEL R. STAPLETON, PH.D. (the “Employee”).

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