0001104659-03-011831 Sample Contracts

CONFIDENTIAL TREATMENT AMENDMENT NO. 2 to the MANUFACTURING AND SUPPLY AGREEMENT entered into as of September 30, 2001 by and between ACS Dobfar, SpA and Cubist Pharmaceuticals, Inc.
Confidential Treatment • June 6th, 2003 • Cubist Pharmaceuticals Inc • Pharmaceutical preparations

This AMENDMENT NO. 2 (“Amendment No. 2”), to that certain Manufacturing and Supply Agreement (the “Agreement”) entered into as of September 30, 2001, is made this 12th day of February, 2003, by and between ACS Dobfar, SpA, an Italian corporation (“ACSD”) and Cubist Pharmaceuticals, Inc., a Delaware corporation (“Cubist”). Unless otherwise defined herein, capitalized terms used but not defined herein shall have the meaning set forth in the Agreement, and the Agreement shall be amended to incorporate any additional definitions provided for in this Amendment No. 1, including definitions in the preamble and recitals hereto.

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