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0001104659-03-028994 Sample Contracts

REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • December 19th, 2003 • Sepracor Inc /De/ • Pharmaceutical preparations • New York

THIS REGISTRATION RIGHTS AGREEMENT dated as of December 12, 2003 among Sepracor Inc., a Delaware corporation (the “Company”), and Morgan Stanley & Co. Incorporated, U.S. Bancorp Piper Jaffray Inc. and Credit Suisse First Boston LLC (the “Initial Purchasers”), is entered into pursuant to the Purchase Agreement dated December 8, 2003 (the “Purchase Agreement”), among the Company and the Initial Purchasers. In order to induce the Initial Purchasers to enter into the Purchase Agreement, the Company has agreed to provide the registration rights set forth in this Agreement.

SEPRACOR INC. as Issuer AND JPMORGAN CHASE BANK as Trustee
Indenture • December 19th, 2003 • Sepracor Inc /De/ • Pharmaceutical preparations • New York

INDENTURE dated as of December 12, 2003 between Sepracor Inc., a Delaware corporation, as issuer (hereinafter sometimes called the “Company”, as more fully set forth in Section 1.1), and JPMorgan Chase Bank, a banking corporation organized under the laws of the State of New York, as trustee (hereinafter sometimes called the “Trustee”, as more fully set forth in Section 1.1).