0001104659-03-029050 Sample Contracts

MASTER AMENDMENT AGREEMENT
Master Amendment Agreement • December 22nd, 2003 • Medimmune Inc /De • Biological products, (no disgnostic substances)

This Master Amendment Agreement (the “Master Amendment”), is entered into as of September 30, 2003 (the “Master Amendment Effective Date”), by and between MedImmune Vaccines, Inc. (formerly Aviron), a Delaware corporation (“MedImmune”), and Wyeth (formerly known as American Home Products Corporation), a Delaware corporation acting through its Wyeth Pharmaceuticals division (“Wyeth”).

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3rd AMENDMENT TO THE DISTRIBUTION AGREEMENT
Distribution Agreement • December 22nd, 2003 • Medimmune Inc /De • Biological products, (no disgnostic substances)

This Third Amendment to the Distribution Agreement (“AGREEMENT”), is entered into as of July 1, 2003 by and between MedImmune, Inc., a Delaware Corporation, having its principal place of business at 35 West Watkins Mill Road, Gaithersburg, MD 20878 (“MEDIMMUNE”) and Abbott International, Ltd., a Delaware Corporation, having its principal place of business at 200 Abbott Park Road, Abbott Park, IL 60064.

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