0001104659-04-007271 Sample Contracts

EXENATIDE MANUFACTURING AGREEMENT
Exenatide Manufacturing Agreement • March 12th, 2004 • Amylin Pharmaceuticals Inc • Pharmaceutical preparations • New York

THIS AGREEMENT effective October 1, 2003, the (“Effective Date”) is made by and between Amylin Pharmaceuticals, Inc., a Delaware corporation having a principal place of business at 9360 Towne Centre Drive, Suite 110, San Diego, California 92121 (“AMYLIN”) and Mallinckrodt Inc., a Delaware corporation, having a principal place of business at 675 McDonnell Blvd., St. Louis, Missouri 63134 (“MALLINCKRODT”).

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SUBLEASE
Sublease • March 12th, 2004 • Amylin Pharmaceuticals Inc • Pharmaceutical preparations

THIS SUBLEASE is made and entered into this 24th day of November, 2003, by and between BRISTOL-MYERS SQUIBB COMPANY, a Delaware corporation (“Sublandlord”) and AMYLIN PHARMACEUTICALS, INC., a Delaware corporation (“Subtenant”).

LEASE AGREEMENT
Lease Agreement • March 12th, 2004 • Amylin Pharmaceuticals Inc • Pharmaceutical preparations

THIS LEASE AGREEMENT (this “Lease”) is dated, for reference purposes only, as of 14th day of November, 2003, between ARE-9363/9373/9393 TOWNE CENTRE, LLC, a Delaware limited liability company (“Landlord”), and AMYLIN PHARMACEUTICALS, INC., a Delaware corporation (“Tenant”).

Commercial Supply Agreement for Exenatide
Commercial Supply Agreement for Exenatide • March 12th, 2004 • Amylin Pharmaceuticals Inc • Pharmaceutical preparations • California

This Agreement, effective as of December 23, 2003, is made by and among Amylin Pharmaceuticals, Inc. (“Amylin”) having a principal place of business at 9360 Towne Centre Drive, San Diego, CA 92121, and Bachem, Inc., a California corporation (“Bachem”), having a principal place of business at 3132 Kashiwa Street, Torrance, CA 90505. References to any of Amylin or Bachem includes reference to their respective Affiliates.

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