0001104659-04-022811 Sample Contracts

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • August 6th, 2004 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • California

THIS SECURITIES PURCHASE AGREEMENT (the “Agreement”), dated as of June 4, 2004, is made and entered into by and between Elan Pharmaceutical Investments II, Ltd., a Bermuda exempted company limited by shares (the “Seller”), and Isis Pharmaceuticals, Inc., a Delaware corporation (the “Purchaser”).

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