0001104659-04-029734 Sample Contracts

INCENTIVE STOCK OPTION AGREEMENT UNDER THE ANIKA THERAPEUTICS, INC. 2003 STOCK OPTION AND INCENTIVE PLAN
Incentive Stock Option Agreement • October 5th, 2004 • Anika Therapeutics Inc • Biological products, (no disgnostic substances)

Pursuant to the Anika Therapeutics, Inc. 2003 Stock Option Incentive Plan (the “Plan”) as amended through the date hereof, Anika Therapeutics, Inc. (the “Company”) hereby grants to the Optionee named above an option (the “Stock Option”) to purchase on or prior to the Expiration Date specified above all or part of the number of shares of Common Stock, par value $.01 per share (the “Stock”) of the Company specified above at the Option Exercise Price per Share specified above subject to the terms and conditions set forth herein and in the Plan.

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Form of Change in Control, Bonus and Severance Agreement
Severance Agreement • October 5th, 2004 • Anika Therapeutics Inc • Biological products, (no disgnostic substances) • Massachusetts

AGREEMENT made as of September 16, 2004 by and among Anika Therapeutics, Inc., a Massachusetts corporation with its principal place of business in Woburn, Massachusetts (the “Company”), and Elizabeth Chen, of Lexington, Massachusetts (the “Executive”), an individual presently employed as the Senior Vice President Marketing and Business Development of the Company.

NON-QUALIFIED STOCK OPTION AGREEMENT FOR COMPANY NON-EMPLOYEE DIRECTORS UNDER THE ANIKA THERAPEUTICS, INC. 2003 STOCK OPTION AND INCENTIVE PLAN
Non-Qualified Stock Option Agreement • October 5th, 2004 • Anika Therapeutics Inc • Biological products, (no disgnostic substances)

Pursuant to the Anika Therapeutics, Inc. 2003 Stock Option and Incentive Plan as amended through the date hereof (the “Plan”), Anika Therapeutics, Inc. (the “Company”) hereby grants to the Optionee named above, who is a Director of the Company but is not an employee of the Company, an option (the “Stock Option”) to purchase on or prior to the Expiration Date specified above all or part of the number of shares of Common Stock, par value $.01 per share (the “Stock”) of the Company specified above at the Option Exercise Price per Share specified above subject to the terms and conditions set forth herein and in the Plan.

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