0001104659-05-001448 Sample Contracts

AMENDED AND RESTATED LOAN AND SECURITY AGREEMENT PNC BANK, NATIONAL ASSOCIATION (AS LENDER AND AS AGENT) WITH BIO-REFERENCE LABORATORIES, INC. AND One or more Subsidiary Parties (BORROWERS) As of September 30, 2004
Security Agreement • January 14th, 2005 • Bio Reference Laboratories Inc • Services-medical laboratories • New Jersey

This Amended and Restated Loan and Security Agreement (this “Agreement”) is dated as of September 30`, 2004 and is by and among BIO-REFERENCE LABORATORIES, INC. (“BRLI”), a New Jersey corporation, having its principal place of business at 481 Edward H. Ross Drive, Elmwood Park, New Jersey 07407 and its Subsidiaries which now or hereafter become a party hereto (the “Subsidiary Parties”) (BRLI and the Subsidiary Parties hereinafter each a “Borrower” and, collectively, “Borrowers”) the financial institutions which are now or which hereafter become a party hereto (collectively, the “Lenders” and individually a “Lender”) and PNC BANK, NATIONAL ASSOCIATION (“PNC”), as agent for Lenders (PNC, in such capacity, the “Agent”).

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AMENDMENT NO. 2
Employment Agreement • January 14th, 2005 • Bio Reference Laboratories Inc • Services-medical laboratories

AMENDMENT NO. 2 dated as of January 7, 2004 to an EMPLOYMENT AGREEMENT entered into as of May 1, 1997 between Bio-Reference Laboratories, Inc., a New Jersey corporation (“the Company”) and Sam Singer (“Employee”) and previously amended as of November 1, 2002 by Amendment No. 1 (the Employment Agreement and Amendment No. 1 collectively referred to as the “Agreement”).

ADDENDUM TO STRATEGIC MARKETING ALLIANCE AGREEMENT
Strategic Marketing Alliance Agreement • January 14th, 2005 • Bio Reference Laboratories Inc • Services-medical laboratories

THIS ADDENDUM TO STRATEGIC MARKETING ALLIANCE AGREEMENT (the “Addendum”) is entered into this 27th day of December, 2004, by and among Roche Diagnostics Corporation, an Indiana corporation, whose primary place of business is located at 9115 Hague Road, Indianapolis, Indiana, 46250 (“RDC”), Bio-Reference Laboratories, Inc., a New Jersey corporation, whose primary place of business is located at 481B Edward Ross Drive, Elmwood Park, New Jersey, 07407 (“BRLI”) and CareEvolve.com, Inc., a New Jersey corporation, whose primary place of business is located at 481B Edward Ross Drive, Elmwood Park, New Jersey, 07407 (“CareEvolve”). (RDC, BRLI and CareEvolve are sometimes referred to herein collectively as the “Parties” and each individually as a “Party.”)

FIFTH AMENDMENT TO LEASE
Bio Reference Laboratories Inc • January 14th, 2005 • Services-medical laboratories • New Jersey

THIS FIFTH AMENDMENT TO LEASE made as of this 16th day of July, 2004 (hereinafter referred to as this “Amendment”), between ALFRED SANZARI ENTERPRISES, L.P., having an office c/o Alfred Sanzari Enterprises, Court Plaza North, 25 Main Street, 6th Floor, Hackensack, New Jersey 07601 (hereinafter referred to as “Landlord”), and BIO-REFERENCE LABORATORIES, INC., a New Jersey corporation, having an office at 481 Edward H. Ross Drive, Elmwood Park, New Jersey 07407 (hereinafter referred to as “Tenant”).

SIXTH AMENDMENT TO LEASE
Lease • January 14th, 2005 • Bio Reference Laboratories Inc • Services-medical laboratories

THIS SIXTH AMENDMENT TO LEASE made as of this 27th day of October, 2004 (hereinafter referred to as this “Amendment”), between ALFRED SANZARI ENTERPRISES, L.P., having an office c/o Alfred Sanzari Enterprises, Court Plaza North, 25 Main Street, 6th Floor, Hackensack, New Jersey 07601 (hereinafter referred to as “Landlord”), and BIO-REFERENCE LABORATORIES, INC., a New Jersey corporation, having an office at 481 Edward H. Ross Drive, Elmwood Park, New Jersey 07407 (hereinafter referred to as “Tenant”).

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