Amendment No. 1 to Rights AgreementRights Agreement • April 8th, 2005 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • Delaware
This Amendment No.1 to Rights Agreement, effective as of April 7, 2005 (“Amendment No.1”), between Isis Pharmaceuticals, Inc., a Delaware corporation (the “Company”), and American Stock Transfer & Trust Company (the “Rights Agent”), provides as follows:
