0001104659-05-029830 Sample Contracts

AMENDMENT NO. 1 TO COMMON STOCK PURCHASE WARRANT
Common Stock Purchase Warrant • June 27th, 2005 • Exact Sciences Corp • Services-commercial physical & biological research

This AMENDMENT NO. 1 TO COMMON STOCK PURCHASE WARRANT (the “Amendment”) is entered into as of June 24, 2005 by and among EXACT Sciences Corporation, a Delaware corporation (the “Company”) and Laboratory Corporation of America Holdings, Inc. as the holder of the Company’s Common Stock Purchase Warrant issued on June 26, 2002 (the “Warrant”).

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