0001104659-05-037833 Sample Contracts

AGREEMENT FOR PURCHASE AND SALE OF 2280 Faraday Avenue San Diego, CA 92008 June 28, 2005
Purchase and Sale Agreement • August 9th, 2005 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • California

THIS AGREEMENT FOR PURCHASE AND SALE is made and entered into as of June 28, 2005 (the “Effective Date”) by and between ISIS PHARMACEUTICALS, INC., a Delaware corporation (“Seller”), and ELECTRO SURFACE TECHNOLOGY, INC., a California corporation (“Buyer”).

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COLLABORATIVE RESEARCH AGREEMENT
Collaborative Research Agreement • August 9th, 2005 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • New York

This LICENSE AND ROYALTY AGREEMENT (“Agreement”) is entered into as of May 24, 2005 (the “Effective Date”) by and between PFIZER INC and its Affiliates (“Pfizer”), a Delaware corporation, having an office at 235 East 42nd Street, New York, New York 10017 and ISIS PHARMACEUTICALS, INC. (“Isis”), a Delaware corporation, having an office at 1896 Rutherford Road, Carlsbad, CA 92008;

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