0001104659-05-052511 Sample Contracts

AMENDMENT NO. 2 TO AMENDED AND RESTATED COLLABORATION AGREEMENT BETWEEN GENZYME CORPORATION AND DYAX CORP.
Collaboration Agreement • November 4th, 2005 • Dyax Corp • Services-commercial physical & biological research

This Amendment No. 2 (the “Second Amendment”) to the Amended and Restated Collaboration Agreement dated May 31, 2002, as previously amended (the “Agreement”) by and between Genzyme Corporation, with its principal office at 500 Kendall Street, Cambridge, Massachusetts, 02142 (“Genzyme”), and Dyax Corp., with a principal office at 300 Technology Square, Cambridge, Massachusetts 02139 (“Dyax”) is effective as of January 1, 2005 (“Amendment Effective Date”). Terms not otherwise defined herein shall have the respective meanings attributed to them in the Agreement.

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