0001104659-06-017254 Sample Contracts

BNP ASSAY DEVELOPMENT, MANUFACTURE AND SUPPLY AGREEMENT
BNP Assay Development, Manufacture and Supply Agreement • March 16th, 2006 • Biosite Inc • In vitro & in vivo diagnostic substances • California

THIS BNP ASSAY DEVELOPMENT, MANUFACTURE AND SUPPLY AGREEMENT (this “Agreement”) effective as of June 24, 2003 (the “Effective Date”), is entered into by and between BIOSITE INCORPORATED, a Delaware corporation (“Biosite”), having a place of business at 11030 Roselle Street, Suite D, San Diego, California 92121, and BECKMAN COULTER, INC., a Delaware corporation (“Beckman”), having a place of business at 4300 N. Harbor Boulevard, Fullerton, California 92834-3100.

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DISTRIBUTION AGREEMENT
Distribution Agreement • March 16th, 2006 • Biosite Inc • In vitro & in vivo diagnostic substances • California

THIS DISTRIBUTION AGREEMENT (this “Agreement”) effective as of January 1, 2006 (the “Effective Date”), is entered into between BIOSITE INCORPORATED, a corporation under the laws of the State of Delaware (“Biosite”), having a place of business at 9975 Summers Ridge Road, San Diego, California 92121, and FISHER SCIENTIFIC COMPANY L.L.C., a Delaware Limited Liability Company represented by its FISHER HEALTHCARE division, (“FHC”), having a place of business at 9999 Veterans Memorial Drive, Houston, Texas 77038.

SEMI-EXCLUSIVE BNP DIAGNOSTIC LICENSE AGREEMENT between BIOSITE DIAGNOSTICS INCORPORATED and SCIOS INC.
Semi-Exclusive License Agreement • March 16th, 2006 • Biosite Inc • In vitro & in vivo diagnostic substances • California

THIS LICENSE AGREEMENT (the “Agreement”) is made effective the 30th day of December, 1996 (the “Effective Date”), by and between BIOSITE DIAGNOSTICS INCORPORATED, a corporation organized under the laws of Delaware with its principal place of business at 11030 Roselle Street, San Diego, California 92121 (“Biosite”), and SCIOS INC., a corporation organized under the laws of the State of Delaware with a principal place of business at 2450 Bayshore Parkway, Mountain View, California 94043 (“Scios”).

AMENDMENT NO. 2 TO SEMI-EXCLUSIVE BNP DIAGNOSTIC LICENSE AGREEMENT
Semi-Exclusive BNP Diagnostic License Agreement • March 16th, 2006 • Biosite Inc • In vitro & in vivo diagnostic substances • California

THIS AMENDMENT NO. 2 TO SEMI-EXCLUSIVE BNP DIAGNOSTIC LICENSE AGREEMENT (this “Amendment”), dated as of August 30, 2002 (the “Amendment Date”), is entered into between BIOSITE INCORPORATED, a Delaware corporation (“Biosite”), having a place of business located at 11030 Roselle Street, Suite D, San Diego, California 92121, and SCIOS INC., a Delaware corporation (“Scios”), having a place of business at 2450 Bay Shore Parkway, Mountain View, California 94043.

FIRST AMENDMENT TO SEMI-EXCLUSIVE BNP DIAGNOSTIC AGREEMENT between BIOSITE DIAGNOSTICS INCORPORATED and SCIOS INC.
Semi-Exclusive BNP Diagnostic Agreement • March 16th, 2006 • Biosite Inc • In vitro & in vivo diagnostic substances

THIS FIRST AMENDMENT TO SEMI-EXCLUSIVE BNP DIAGNOSTIC AGREEMENT is entered into as of August 1, 1997 between BIOSITE DIAGNOSTICS INCORPORATED, a corporation organized under the laws of Delaware with its principal place of business at 11030 Roselle Street, San Diego, California 92121 (“Biosite”), and SCIOS INC., a corporation organized under the laws of Delaware with a principal place of business at 2450 Bayshore Parkway, Mountain View, California 94043 (“Scios”);

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