0001104659-06-066213 Sample Contracts

SIXTH LOAN MODIFICATION AGREEMENT
Sixth Loan Modification Agreement • October 12th, 2006 • Collagenex Pharmaceuticals Inc • Pharmaceutical preparations

This Sixth Loan Modification Agreement (this “Loan Modification Agreement’) is entered into as of October 9, 2006, by and between SILICON VALLEY BANK, a California-chartered bank, with its principal place of business at 3003 Tasman Drive, Santa Clara, California 95054 (“Bank”) and COLLAGENEX PHARMACEUTICALS, INC., a Delaware corporation with its chief executive office located at 41 University Drive, Newtown, Pennsylvania 18940 (“Borrower”).

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