0001104659-06-071852 Sample Contracts

MANUFACTURING, COMMERCIALIZATION AND DEVELOPMENT AGREEMENT
Manufacturing, Commercialization and Development Agreement • November 7th, 2006 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • Delaware

THIS MANUFACTURING, COMMERCIALIZATION AND DEVELOPMENT AGREEMENT (this “Agreement”) is entered into as of July 31, 2006 (the “Effective Date”) between ISIS PHARMACEUTICALS, INC., a Delaware corporation, through its IBIS BIOSCIENCES division (“Ibis”), and BRUKER DALTONICS INC., a Delaware corporation (“Bruker”).

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